Motif ID: STAT5{A,B}.p2

Z-value: 0.704


Transcription factors associated with STAT5{A,B}.p2:

Gene SymbolEntrez IDGene Name
STAT5A 6776 signal transducer and activator of transcription 5A
STAT5B 6777 signal transducer and activator of transcription 5B

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
STAT5Achr17_+_37693090-0.457.8e-02Click!
STAT5Bchr17_-_37681917-0.058.5e-01Click!


Activity profile for motif STAT5{A,B}.p2.

activity profile for motif STAT5{A,B}.p2


Sorted Z-values histogram for motif STAT5{A,B}.p2

Sorted Z-values for motif STAT5{A,B}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT5{A,B}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_49552638 1.634 NM_001083335
NM_013380
 ZFP112

zinc finger protein 112 homolog (mouse)

chr19_+_49248003 1.539 NM_013361
 ZNF223
zinc finger protein 223
chr19_+_39860398 1.456 NM_001012320
NM_018443
 ZNF302

zinc finger protein 302

chr6_-_27548438 1.389 NM_007149
 ZNF184
zinc finger protein 184
chr19_-_49309102 1.358 LOC100379224
hypothetical LOC100379224
chr19_+_42099073 1.317 NM_198539
 ZNF568
zinc finger protein 568
chr19_+_49290319 1.291 NM_013398
 ZNF224
zinc finger protein 224
chr19_+_49180171 1.273 NM_003445
NM_198089
 ZNF155

zinc finger protein 155

chr10_-_121345968 1.204 TIAL1
TIA1 cytotoxic granule-associated RNA binding protein-like 1
chr19_+_49361054 1.184 NM_001146220
NM_001032373
NM_001032374
NM_015919
NM_001032372
 ZNF226




zinc finger protein 226




chr19_+_42033106 1.149 NM_003419
 ZNF345
zinc finger protein 345
chr19_-_42098758 1.144 NM_001171979
 ZNF829
zinc finger protein 829
chr10_-_98315090 1.142 TM9SF3
transmembrane 9 superfamily member 3
chr19_+_42400908 1.135 ZNF383
zinc finger protein 383
chr19_-_49131250 1.125 NM_003425
 ZNF45
zinc finger protein 45
chr19_+_49198916 1.102 NM_006300
 ZNF230
zinc finger protein 230
chr5_+_178219519 1.081 NM_058230
 ZNF354B
zinc finger protein 354B
chr1_-_219977424 1.079 NM_144728
 DUSP10
dual specificity phosphatase 10
chr19_+_49309350 1.078 NM_013362
 ZNF225
zinc finger protein 225
chr19_-_62781883 1.036 NM_017879
 ZNF416
zinc finger protein 416

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
2.27 3.64e-11 GO:0006355 regulation of transcription, DNA-dependent
2.18 3.42e-10 GO:0051252 regulation of RNA metabolic process
2.13 3.27e-10 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.10 6.06e-10 GO:0010556 regulation of macromolecule biosynthetic process
2.04 3.60e-09 GO:0010468 regulation of gene expression
1.97 7.28e-09 GO:0051171 regulation of nitrogen compound metabolic process
1.97 1.42e-08 GO:0009889 regulation of biosynthetic process
1.97 1.79e-08 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.97 1.79e-08 GO:0031326 regulation of cellular biosynthetic process
1.80 1.22e-07 GO:0060255 regulation of macromolecule metabolic process
1.73 6.94e-07 GO:0031323 regulation of cellular metabolic process
1.72 1.36e-06 GO:0080090 regulation of primary metabolic process
1.65 3.47e-06 GO:0019222 regulation of metabolic process
1.33 3.42e-03 GO:0050794 regulation of cellular process
1.29 4.95e-03 GO:0065007 biological regulation
1.28 2.61e-02 GO:0050789 regulation of biological process

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.67 4.55e-13 GO:0005634 nucleus
1.45 8.04e-15 GO:0043231 intracellular membrane-bounded organelle
1.45 9.51e-15 GO:0043227 membrane-bounded organelle
1.41 8.02e-16 GO:0043229 intracellular organelle
1.41 1.08e-15 GO:0043226 organelle
1.29 6.52e-12 GO:0044424 intracellular part
1.27 9.43e-11 GO:0005622 intracellular
1.09 9.72e-03 GO:0044464 cell part
1.09 9.84e-03 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
2.52 2.94e-16 GO:0008270 zinc ion binding
2.39 3.31e-16 GO:0046914 transition metal ion binding
2.30 2.54e-14 GO:0003677 DNA binding
1.89 9.59e-11 GO:0003676 nucleic acid binding
1.77 3.74e-10 GO:0046872 metal ion binding
1.75 8.65e-10 GO:0043169 cation binding
1.74 1.04e-09 GO:0043167 ion binding